Rapid Delivery for Hamamelis Virginiana Little Suzie - CDP-CHOLINE – Tong Rui Bio Detail:
Name：CDP-CHOLINE,CITICOLINE
Chemical name：cytidine5’-diphosphatecholine
Molecular Formula：C14H26N4O11P2
CAS:987-78-0
Einecs NO:213-580-7
Formula Weight:488.33
Apearance: Off white powder.
Purity：98%
Chemical name：cytidine5’-diphosphatecholine
Molecular Formula：C14H26N4O11P2
CAS:987-78-0
Einecs NO:213-580-7
Formula Weight:488.33
Apearance: Off white powder.
Purity：98%
Citicoline (INN), also known as cytidine diphosphate-choline (CDP-Choline) or cytidine 5′-diphosphocholine is nootropic. It is an intermediate in the generation of phosphatidylcholine from choline.
Studies suggest that CDP-choline supplements increase dopamine receptor densities, and suggest that CDP-choline supplementation helps prevent memory impairment resulting from poor environmental conditions. Preliminary research has found that citicoline supplements help improve focus and mental energy and may possibly be useful in the treatment of attention deficit disorder.
Citicoline has also been shown to elevate ACTH independently from CRH levels and to amplify the release of other HPA axis hormones such as LH, FSH, GH and TSH in response to hypothalamic releasing factors. These effects on HPA hormone levels may be beneficial for some individuals but may have undesirable effects in those with medical conditions featuring ACTH or cortisol hypersecretion including PCOS, type II diabetes and major depressive disorder.
Studies suggest that CDP-choline supplements increase dopamine receptor densities, and suggest that CDP-choline supplementation helps prevent memory impairment resulting from poor environmental conditions. Preliminary research has found that citicoline supplements help improve focus and mental energy and may possibly be useful in the treatment of attention deficit disorder.
Citicoline has also been shown to elevate ACTH independently from CRH levels and to amplify the release of other HPA axis hormones such as LH, FSH, GH and TSH in response to hypothalamic releasing factors. These effects on HPA hormone levels may be beneficial for some individuals but may have undesirable effects in those with medical conditions featuring ACTH or cortisol hypersecretion including PCOS, type II diabetes and major depressive disorder.
Certificate of Analysis
| Product Information | |
| Product Name: | Citicoline(CDP-Choline) |
| CAS No.: | 987-78-0 |
| Molecular formula: | C14H26N4O11P2 |
| Batch No. | TRB-CDP-20190620 |
| MFG Date: | June 20,2019 |
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Item |
Specification | Test Results |
| Active Ingredeints | ||
| Assay(%.On Dried Base) | 98.0%~102.0% by HPLC | 100.30% |
| Physical Control | ||
| Appearance | Fine crystalline Powder | Complies |
| Color | White to Off White |
Complies |
| Identification | NMR |
Complies |
| PH | 2.5~3.5 |
3.3 |
| Loss on Drying | 1.0% Max | 0.041% |
| Water | 1.0% Max | 0.052% |
| 5’-CMP | NMT1.0% | 0.10% |
| Chemical Control | ||
| Heavy metals | NMT10PPM |
Complies |
| Arsenic(As2O3) | NMT1PPM |
Complies |
| Sulfate(SO4) | NMT 0.020% |
Complies |
| Iron(Fe) | NMT10PPM |
Complies |
| Chloride(Cl) | NMT 0.020% |
Complies |
| Solvent Residual | Meeting EU/USP Standard |
Complies |
| Microbiological Control | ||
| Total Plate Count | 10,00cfu/g Max |
Complies |
| Yeast & Mold | 100cfu/g Max |
Complies |
| E.Coli | Negative/10g |
Complies |
| Salmonella sp. | Negative/25g |
Complies |
| Staph Aureus | Negative/10g |
Complies |
| Pseudomonas aeruginosa | Negative/25g |
Complies |
| Packing and Storage | ||
| Packing | Pack in paper-drums. 25Kg/Drum 1Kg per plastic bag | |
| Storage | Store in a well-closed container away from moisture and direct sunlight. | |
| Shelf Life | 2 years if sealed and stored properly. | |
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More information of TRB |
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| Regulation certification | ||
| U.S.FDA,CEP,KOSHER HALAL GMP ISO Certificates | ||
| Reliable Quality | ||
| Nearly 20 years,export 40 countries and regions,more than 2000 batches produced by TRB have no any quality problems,unique purification process,impurity and purity control meet USP,EP and CP | ||
| Comprehensive Quality System | ||
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▲Quality Assurance System |
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| ▲ Validation System |
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| ▲ Training System |
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| ▲ Internal Audit Protocol |
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| ▲ Suppler Audit System |
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| ▲ Equipment Facilities System |
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| ▲ Material Control System |
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| ▲ Production Control System |
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| ▲ Packaging Labeling System |
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| ▲ Laboratory Control System |
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| ▲ Verification Validation System |
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| ▲ Regulatory Affairs System |
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| Control Whole Sources and Processes | ||
| Strictly controlled all raw material,accessories and packaging materials.Preferred raw materials and accessories and packaging materials supplier with U.S. DMF number.Several raw material suppliers as supply assurance. | ||
| Strong Cooperative Institutions to support | ||
| Institute of botany/Institution of microbiology/Academy of Science and Technology/University | ||
Product detail pictures:
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We support our purchasers with ideal premium quality products and substantial level company. Becoming the specialist manufacturer in this sector, we've acquired rich practical working experience in producing and managing for Rapid Delivery for Hamamelis Virginiana Little Suzie - CDP-CHOLINE – Tong Rui Bio, The product will supply to all over the world, such as: Muscat, venezuela, Durban, Based on our guiding principle of quality is the key to development, we continually strive to exceed our customers' expectations. As such, we sincerely invite all interested companies to contact us for future cooperation, We welcome old and new customers to hold hands together for exploring and developing; For more information, be sure to feel free to contact us. Thanks. Advanced equipment, strict quality control, customer-orientation service, initiative summary and improvement of defects and extensive industry experience enable us to guarantee more customer satisfaction and reputation which, in return, brings us more orders and benefits. If you are interested in any of our merchandise, make sure you feel free to contact us. Inquiry or visit to our company are warmly welcome. We sincerely hope to start a win-win and friendly partnership with you. You can see more details in our website.
By Hazel from Tanzania - 2015.10.09 19:07
This enterprise in the industry is strong and competitive, advancing with the times and develop sustainable, we are very pleased to have a opportunity to cooperate!
By Faithe from Croatia - 2015.12.22 12:52
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