Apigenin 98%

Apigenin, as a known bioflavonoid, has been shown to exhibit various biological activities, including antioxidant, anti-inflammatory, antitumor, ant-genotoxic, anti-allergic, neuroprotective, cardioprotective, and antimicrobial.However, One of the most frequent sources of apigenin is celery (Apium graveolens), a marsh plant in the family of Apiaceae that has been cultivated as a vegetable since antiquity. Apigenin is the most extracted nutrient in celery, containing 108 mg apigenin per kg.Apigenin is one of the common dietary flavonoids, which is abundantly found in many fruits, vegetables, and medicinal herbs. It serves various physiological functions, such as antioxidant, potent anti-inflammatory, antiviral activities, antibacterial and blood pressure reduction.

Product Name: Celery lau extract Apigenin 98%

Lakina Name: Apium graveolens L.

CAS No: 520-36-5

Plant Part Used: lau

'Oponopono: Apigenin

Mea o loko: Apigenin 98,0% ma HPLC

Kala: Brown i yellow ka pauka me ka ano ala a me kaʻaiʻana

GMO you: GMO Free

Hāʻawe: i 25kgs puluniu pahu

Waho pūnaewele: E ipu unopened i ka me, maloo wahi, E aku mai ka ikaika kukui

Holopapa Life: 24 mahina mai ka la aku o ka? Iecaianoaaiiuo

Anati-ʻeho ai

Apigenin Radio he nui kūlana i ka maʻi 'aʻai Kāohiʻana ma ka inducing apoptosis i loko o kekahi mau aeea laina.

Ovarian Ka maʻi 'aʻai:

Kekahi noiʻi i loaʻa ia apigenin ke inhibit i ka ulu, ka hoʻonuiʻana, a me ka hoolilo ana o CA-ov3 (kanaka ovarian Ka maʻi 'aʻai aeea); ka mea, induces apoptosis o CA-ov3 ma ka malama ana i ka maʻi 'aʻai keena stasis ma ka G2 / M pae. Ke hookoia ua pili i ka manawa a me ka mahele lāʻau.

Pancreatic Ka maʻi 'aʻai:

Apigenin hiki inhibit i ka ka hoʻonuiʻana o pancreatic Ka maʻi 'aʻai keena. Apigenin starves kaʻeho ma ka hoemi i ke kumu o ka monakō koko, i mea o kaʻai ma luna a maʻi 'aʻai keena ola. Oae, Apigenin ke hoʻoikaika i ka laulā o ka chemotherapy drug- gemcitabine.

Chemo-sensitization

Ua Ua loaʻa i apigenin i haʻahaʻa ka maʻiʻo i ka haʻahaʻa cytotoxic ia, a hiki ole induce kanaka huʻi myeloid leukemia (HL-60) aeee e apoptosis ka pono. Eia naʻe, apigenin hiki ka hōʻoi 'i ka inhibitory hopena o ka cisplatin (DDP) ma luna o HL-60 aeea ka hoʻonuiʻana ana hoʻohuiʻia me kekahi mau nā hoʻohui like o DDP. A Apigenin ke i chemotherapy-sensitization kanawai ma HL-60; hiki i Low nā hoʻohui like o apigenin emi i ka ia'ku o HL-60 aeee i chemotherapy-ʻonou apoptosis, a hiki e pili ana i ka ia-rula o NF-κB a me BCL-2. (NF-KB mea heʻano o ka kumuʻiʻo eiiieaena e hoʻi iā DNA Ekolu a, ka? Iecaianoaaiiie o cytokines a me ke kelepona hele ola; BCL2 ua encoded i loko o ke kino ma ka BCL2'ōewe, ka mea, o ka mua hoa o ka BCL2 hoʻokonukonu nā polokina 'ohana i hiki hooponopono aeea make)

ake hoomalu ana

Apigenin ke emi ake ino e poloʻai pule ma ka ischemia-reperfusion ma antagonizing lipid peroxidation a scavenging noa radicals.

Apigenin hiki emi ake ino, kena ae la ia e oxidative stress no i kona potent antioxidant a me Anati-hoʻoʻino hana.

Pharmacological ho okolohua Ua hooiaio ia apigenin mai he maopopo aiiay ia ma luna o ka waiʻona-e poloʻai pule ake / hepatocyte poino, a me kona iniiaiieʻano papa hana ua pili i ka inhibition o CYP2E1 olelo i loko o ke akepaʻa / hepatocyte.

pale ai osteoporosis

Apigenin inhibits osteoblastogenesis, osteoclastogenesis, a me kekahi 'ano ua ālai iwi me keia poho.

Apigenin i malama ma ka hoemi iwi lilo ana i loko o ke kino iwi'aʻaʻa.

Kekahi haʻawina e pili pū ana i ka MC3T3-E1, he osteoblast precursor aeea laina loko mai o Mus musculus (iole) calvaria, ike ia apigenin ke inhibit ka TNF-α, IFN-γ, a laila, e poloʻai i ka secretion o kekahi mau cytokines e paipai osteoclast ho okumu.

Apigenin kekahi inhibited ka differentiation o 3T3-L1 adipose precursor aeee i loko o adipocytes ikaika, nolaila, inhibiting ka differentiation kahu inhibition adipocyte differentiation-ʻonou IL-6, MCP-1, lectin huahana.

Apigenin inhibits ka differentiation o osteoclasts mai RAW264.7 aeea laina, a laila inhibits ke kahua o multinucleated osteoclasts. Ua hiki no hoi induce osteoclast apoptosis a inhibit iwi resorption.

Anati-hoʻoʻino a me Anati-oxidant ha awina

Apigeninʻuʻumi iho i ka li nui kaʻina hana, maoli ka IL-10 pae a normalizes ka oxidative stress kiko'î

Apigenin inhibits kākoʻo-hoʻoʻino cytokines a induces ka Anati-hoʻoʻino cytokine? Iecaianoaaiiuo.

Kekahi moʻokalaleo paipai ia apigenin alleviates'aʻaʻa li nui e poloʻai pule ma oxidative stress i loko o nā'aʻaʻa ma pē mālie likeʻole oxidative stress hōʻailona, ​​interleukins, koko'ūhū hōʻailona, ​​a me ka olelo ana o kekahi mau 'ē aʻe nā nā'ūhū.

Hooponopono o ka endocrine

Apigenin hiki hooponopono koko kōpaʻa, pono thyroid insufficiency a me ka pāʻana lipid peroxidation.It i loaʻa ia apigenin ke hoomahuahua i ka pae o ka insulina a me ka thyroxine ma diabetic holoholona, ​​a emi iho i ka lehulehu o ke koko kō a me ka ha awina o ka monakō koko-6-phosphorylase (G- 6-Pase).

Apigenin nana e hoole i ka hopena o ka mahuahua lāʻau lapaʻau naʻokoko, mahuahua ake lipid peroxidation (LPO) a ua hoʻemi hana o antioxidants e like me catalase (popoki) a me ka superoxide dismutase (ho'āno) i loko o alloxan-ʻonou holoholona.

Ma na holoholona me ka regular koko kōpaʻa, apigenin hiki no hoi ho'ēmi i lāʻau lapaʻau naʻokoko, a ake lipid peroxidation, a me ka hoomahuahua i ka ha awina o antioxidants ma keena.

Pharmacological waiwai o ka apigenin

Apigenin ua, ua pili nui i loko o nā makahiki, e like me ka pono ola ka mea hoʻopaipai ma no o kona lalo kūʻiʻoo kaʻawahia a me kona ola 'ole ma regular kū'ē Ka maʻi' aʻai keena, like me nā structurally pili flavonoids. Aia ua he bulk o ka noiʻi hōʻike mea i hōʻike apigenin mea nui pākōleaʻia no ka maʻi he nui

Launch:

-Inhibit i ka ulu ana o Ka maʻi 'aʻai keena.

-Lower ke koko,

-Protects ka mea'ōnaehana mānowai koko'ōnaehana

-Help hiamoe, malie nä olonä, hoʻopau irritability

-Resist aat

-Prevent osteoporosis

-Diuretic hopena.

-Inhibit platelet aggregation.

palapala noi:

-Medicine field, Health care field