ʻO kahi hui kūlohelohe i loaʻa i nā strawberry a me nā huaʻai a me nā huaʻai hiki ke kōkua i ka pale ʻana i ka maʻi ʻo Alzheimer a me nā maʻi neurodegenerative pili i ka makahiki, e hōʻike ana kahi noiʻi hou.
Ua ʻike nā kānaka noiʻi mai ka Salk Institute no Biological Studies ma La Jolla, CA, a me nā hoa hana ʻo ka mālama ʻana i nā mole o ka ʻelemakule me ka fisetin i hoʻemi ʻia ka emi o ka noʻonoʻo a me ka hoʻowalewale ʻana o ka lolo.
ʻO Pamela Maher, ka mea kākau moʻolelo ʻoi loa, o ka Cellular Neurobiology Laboratory ma Salk, a me nā hoa hana i hōʻike i kā lākou loaʻa ma The Journals of Gerontology Series A.
ʻO Fisetin kahi flavanol i loaʻa i nā hua like ʻole a me nā mea kanu, e like me nā strawberry, persimmons, ʻāpala, hua waina, ʻaka, a me nā kukama.
ʻAʻole wale ʻo fisetin e hana ma ke ʻano he mānoanoa kala no nā huaʻai a me nā mea kanu, akā ua hōʻike pū ʻia kekahi mau noiʻi i ka loaʻa ʻana o ka waiwai antioxidant i ka mea i hoʻohui ʻia, ʻo ia hoʻi he hiki ke kōkua i ka hōʻemi ʻana i ka pohō o ka cell i hana ʻia e nā radical manuahi. Ua hōʻike ʻia ʻo Fisetin e hoʻoliʻiliʻi i ka lī.
I loko o nā makahiki he 10 i hala aku nei, ua alakaʻi ʻo Maher a me nā hoa i kekahi mau noiʻi e hōʻike ana i ka hiki ke kōkua i nā antioksant a me nā anti-inflammatory o ka fisetin e pale aku i nā hunaola o ka lolo i nā hopena o ka ʻelemakule.
ʻO kekahi o ia ʻano noi, i paʻi ʻia ma 2014, ua ʻike ʻo fisetin e hoʻemi ana i ka nalo ʻana o ka hoʻomanaʻo ʻana i nā hiʻohiʻona iole o ka maʻi ʻo Alzheimer. Eia nō naʻe, ua nānā ka nānā ʻana i nā hopena o ka lawaiʻa i loko o nāʻiole me ka ʻohana Alzheimer, kahi a nā kānaka noiʻi e hoʻomaopopo ai he 3 mau pākēneka wale nō o nā hihia Alzheimer āpau.
No ke aʻo hou, ua ʻimi ʻo Maher a me ka hui e ʻike inā loaʻa paha nā pōmaikaʻi i ka fisetin no ka maʻi sporadic Alzheimer, ʻo ia ka ʻano maʻamau i kū aʻe me ka makahiki.
No ka hōʻea ʻana i kā lākou ʻike, ua hoʻāʻo ka poʻe noiʻi i ka fisetin i nā ʻiole i hana ʻenekini ʻia i ka wā mua, a ua hopena i kahi mole o ka maʻi sporadic Alzheimer
I ka 3 mau mahina o nā ʻiole ʻelemakule prematurely, ua māhele ʻia lākou i ʻelua mau hui. Ua hānai ʻia kahi hui i kahi mahele o ka lawaiʻa me kā lākou meaʻai i kēlā me kēia lā no 7 mau mahina, a hiki i ka makahiki 10. ʻAʻole i loaʻa i ka hui ʻē aʻe ka hui.
Ua wehewehe ka kime ma ka 10 mau makahiki o ke kino, a me ke kūlana noʻonoʻo o nāʻiole i like me nā ʻiole ʻelua makahiki.
Aia nā koʻokoʻo āpau i nā hoʻokolohua noʻonoʻo a me nā ʻano i loko o ke aʻo ʻana, a ua loiloi pū nā mea noiʻi i nā ʻiole no nā pae o nā māka i hoʻopili ʻia i ke koʻikoʻi a me ka mumū.
Ua ʻike nā kānaka noiʻi he 10 mau mahina ʻo ka ʻiole i loaʻa ʻole ka fisetin i hōʻike ʻia ka hoʻonui ʻana o nā māka e pili ana i ke koʻikoʻi a me ka mumū, a ua hana maikaʻi ʻole lākou i nā hoʻokolohua noʻonoʻo ma mua o nāʻiole i mālama ʻia me ka fisetin.
I ka lolo o ka ʻiole mālama ʻole ʻia, ua ʻike nā kānaka noiʻi he ʻelua mau ʻano neurons i kū maʻamau i nā anti-inflammatory - nā astrocytes a me nā microglia - ke hāpai maoli nei i ka pehu. Eia naʻe, ʻaʻole kēia ka hihia no nā ʻiole he 10 mau mahina i mālama ʻia me ka fisetin.
ʻO ka mea hou aku, ua ʻike ka poʻe noiʻi he kūlike ka hana a me ka hana noʻonoʻo o nā ʻiole i mālama ʻia me nā ʻiole i hana ʻole ʻia he 3 mahina.
Manaʻo nā kānaka noiʻi he hiki i kā lākou mea i loaʻa ai ke alakaʻi i kahi papahana pale hou no Alzheimer, a me nā maʻi neurodegenerative pili i ka makahiki.
"Ma muli o kā mākou hana mau, manaʻo mākou he kōkua paha ka fisetin ma ke ʻano he mea pale aku no nā maʻi neurodegenerative e pili ana i nā makahiki, ʻaʻole wale ʻo Alzheimer, a makemake mākou e paipai i ke aʻo ikaika loa ʻana iā ia," wahi a Maher.
Eia naʻe, ua hoʻomaopopo nā kānaka noiʻi he koi ʻia nā hoʻokolohua hoʻokolohua kanaka e hōʻoia i kā lākou hopena. Lana ko lākou manaʻo e hui pū me nā mea noiʻi ʻē aʻe e kū i kēia pono.
“ʻAʻole nāʻiole nā poʻe, ʻoiaʻiʻo. Akā, ua lawa nā mea like a mākou e manaʻo nei e hōʻoia pono ana ka fisetin, ʻaʻole wale no ka mālama ʻana i ka sporadic AD [maʻi ʻo Alzheimer] akā no ka hōʻemi ʻana i kekahi o nā hopena ʻike i pili me ka ʻelemakule, maʻamau. "
Ka manawa Post: ʻAp-18-2020