Gulu lachilengedwe lomwe limapezeka mu strawberries ndi zipatso zina ndi ndiwo zamasamba zitha kuthandiza kupewa matenda a Alzheimer ndi matenda ena okhudzana ndi ukalamba, kafukufuku watsopano akuwonetsa.
Ofufuza kuchokera ku Salk Institute for Biological Study ku La Jolla, CA, ndi anzawo adapeza kuti kuchiza mbewa zakukalamba ndi fisetin zidapangitsa kuchepa kwazidziwitso komanso kutupa kwaubongo.
Wolemba kafukufuku wamkulu Pamela Maher, wa Cellular Neurobiology Laboratory ku Salk, ndi anzawo posachedwapa anena zomwe apeza mu The Journals of Gerontology Series A.
Fisetin ndi flavanol yomwe imapezeka mu zipatso ndi ndiwo zamasamba zosiyanasiyana, kuphatikiza ma strawberries, ma persimmon, maapulo, mphesa, anyezi, ndi nkhaka.
Sikuti fisetin imangokhala ngati utoto wothandizira zipatso ndi ndiwo zamasamba, koma kafukufuku adawonetsanso kuti kampaniyi ili ndi zida za antioxidant, kutanthauza kuti zitha kuthandiza kuchepetsa kuwonongeka kwama cell komwe kumachitika chifukwa cha ma radicals aulere. Fisetin yawonetsedwanso kuti ichepetse kutupa.
Pazaka 10 zapitazi, Maher ndi anzawo adachita kafukufuku wambiri wosonyeza kuti antioxidant ndi anti-inflammatory properties a fisetin itha kuthandiza kuteteza ma cell amubongo motsutsana ndi ukalamba.
Kafukufuku wina, wofalitsidwa mu 2014, adapeza kuti fisetin idachepetsa kukumbukira kukumbukira mu mbewa za matenda a Alzheimer's. Komabe, kafukufukuyu adayang'ana pa zovuta za fisetin mu mbewa ndi banja la Alzheimer's, zomwe ofufuzawo amangowerengera mpaka 3% ya milandu yonse ya Alzheimer's.
Phunziro latsopanoli, Maher ndi gulu adayesetsa kudziwa ngati fisetin itha kukhala ndi phindu la matenda a Alzheimer's sporadic, omwe ndi omwe amafala kwambiri ndi ukalamba.
Kuti apeze zomwe apeza, ofufuzawo adayesa fisetin mu mbewa zomwe zidapangidwa kuti zizikula msanga, zomwe zimapangitsa mtundu wa mbewa wa matenda a Alzheimer's sporadic.
Makoswe okalamba asanakwane anali ndi miyezi itatu, adagawika m'magulu awiri. Gulu limodzi lidadyetsedwa fisetin ndi chakudya chawo tsiku lililonse kwa miyezi 7, mpaka atakwanitsa miyezi 10. Gulu linalo silinalandire kampaniyo.
Gululi limafotokoza kuti pakatha miyezi 10 zakubadwa, mbewa zakuthupi ndi zanzeru za mbewa zinali zofanana ndi mbewa zazaka ziwiri.
Makoswe onse adakumana ndi mayesero ozindikira komanso amachitidwe pakafukufukuyu, ndipo ofufuzawo adawunikanso mbewa zamagulu azizindikiro zomwe zimalumikizidwa ndi kupsinjika ndi kutupa.
Ofufuzawa adapeza kuti mbewa za miyezi 10 zomwe sizinalandire fisetin zikuwonetsa kuchuluka kwa zolembera zomwe zimakhudzana ndi kupsinjika ndi kutupa, ndipo zidachitanso zoyipa kwambiri pakuyesa kuzindikira kuposa mbewa zomwe zimathandizidwa ndi fisetin.
Muubongo wama mbewa omwe sanalandire chithandizo, ofufuzawo adapeza kuti mitundu iwiri ya ma neuron omwe nthawi zambiri amakhala odana ndi zotupa - ma astrocyte ndi microglia - kwenikweni anali kulimbikitsa kutupa. Komabe, sizinali choncho kwa mbewa za miyezi 10 zoyesedwa ndi fisetin.
Kuphatikiza apo, ofufuzawo adapeza kuti magwiridwe antchito ndi kuzindikira kwa mbewa zochiritsidwa zinali zofanana ndi mbewa zosakwaniritsidwa za miyezi itatu.
Ofufuzawo akukhulupirira kuti zomwe apeza zikuwonetsa kuti fisetin imatha kubweretsa njira yatsopano yodzitetezera ku Alzheimer's, komanso matenda ena okhudzana ndi ukalamba.
"Kutengera ntchito yomwe tikugwira, tikuganiza kuti fisetin itha kukhala yothandiza ngati njira yotetezera matenda ambiri okhudzana ndi matenda okhudzana ndi ukalamba, osati Alzheimer's kokha, ndipo tikufuna kulimbikitsa kuphunzira mwakhama," atero a Maher.
Komabe, ofufuzawo akuti mayesero azachipatala amafunikira kuti atsimikizire zotsatira zawo. Akuyembekeza kuphatikizana ndi ofufuza ena kuti akwaniritse zosowazi.
“Mbewa si anthu, ayi. Koma pali kufanana kokwanira komwe tikuganiza kuti fisetin imafuna kuti tiwunikire mozama, osati kungochiza matenda a AD [Alzheimer's] kokha komanso kuchepetsa zina mwazidziwitso zomwe zimakhudzana ndi ukalamba, makamaka. ”
Post nthawi: Apr-18-2020